Upright and Inverted Hybrid Microscope
The IBIXX-1 is a multi-functional, multi-purpose microscope for double-sided sample illumination and observation
Based on the Olympus BX and IX series microscopes, the IBIXX-1 provides the user with unprecedented versatility in configuring scientific experiments using a variety of methods. The microscope provides two ports for upright and inverted full field illumination in transmitted light, as well as in fluorecence. By using objectives with different NA, the sizes of the fields of view illuminated from above and from below can be different, providing the general view of a large portion of the sample from one side (for instance a whole cultured neuron), while allowing the detailed view of a smaller area from the other side (for instance a dendrite branch)
A new level of functionality can be added by using the IBIXX-1 with the Rapp Opto spot and pattern illumination devices, the UGA-42 Firefly and UGA-42-GEO, the μ-Matrix and the AiWon. Now full field imaging from one side of the sample can integrated with localized photostimulation (eg. photoactivation or uncaging) from the other side, allowing the study of the signal transmission across thick samples without the need of expensive 2-photon stimulation to avoid unwanted signals from the intermediate layers.
The flexibility and versatility of the IBIXX-1 microscope makes it a powerful tool in: